Amyloidosis Project ECHO

This virtual interactive clinic offers quarterly 1-hour sessions focused on AL (light chain) and TTR (transthyretin) amyloidosis, two underrecognized but increasingly manageable causes of heart failure and multisystem disease.

Each session includes:

• Brief didactic lectures (20 minutes) on suspicion, diagnosis, and management
• Case-based learning from real-world scenarios (20 min)
• Interactive Q&A (20 min) with amyloidosis specialists

Over the course of the Amyloidosis Project ECHO program, participants will be to:

1. Recognize the clinical red flags for AL and TTR amyloidosis
2. Understand the diagnostic pathways, including lab tests and imaging
3. Apply evidence-based treatment strategies for both AL and TTR types
4. Improve coordination of care with amyloidosis centers and specialists
5. Reduce diagnostic delays and improve patient outcomes

The purpose of the case is to foster discussion and shared learning using a real-world example. By bringing amyloidosis focused real-world cases to the session, everyone that is a part of the ECHO can exchange practical, evidence-based approaches, so learning benefits the entire ECHO community, not just the presenter.

While the specific details may vary on a case-by-case basis, what’s important is to focus on presenting the key details that fully encapsulate the nuances of your case to streamline the overall discussion and learning. Case presenters should typically outline the patient background, key diagnostic and management decisions, any challenges encountered, and questions you may have for the session participants. You will oversee presenting your case in full. Here is a case presentation template to help structure your slides and understand how a case is typically formatted.

Please keep the following in mind when preparing your presentation:

• Patient anonymity is required. Remove or de-identify all personally identifiable information (e.g., name, date of birth, MRN) before submitting or presenting your case.
• When referencing medications, please use generic drug names rather than brand names.

Currently, amyloidosis ECHO sessions are structured into 4 segments:

1. Greetings / Introductions (~10 minutes)
2. Didactic Speaker Presentation / Discussion (~25 minutes)
3. Case Speaker Presentation / Discussion (~20 minutes)
4. Wrap-up (~5 minutes)

Case presenters only need to plan for the speaker presentation segment. Your case presentation should strive to be approximately 5 minutes. After your presentation there will be 10 minutes for clarifying questions from ECHO participants, and a final 5 minutes for recommendations from the specialist panel.

We encourage any healthcare provider who has a case to consider registering for review and presenting it at one of our ECHO sessions. We will be thorough in our review, and follow up if there’s a particular reason we don’t believe your case may not be appropriate to present.

A case doesn’t have to be resolved to be considered adequate for presenting. There needs to be enough information to properly assess the case and create discussion and a learning opportunity from. Regardless of whether the case is unresolved, the anonymity of the patient and the removal of any personal identifiable information is essential.

Any information, data, images, etc. you find relevant to fully explain your amyloidosis diagnosis focused case is acceptable. This includes echocardiograms, technetium PYP scans, or pathology slides. Any identifying information on images will need to be removed or blacked out.

To submit a case, click “Submit for Review” in the Present a Case section of this page, where you’ll be directed to fill out the Amyloidosis Project ECHO Case Presentation Form.

Once your submission has been reviewed, we’ll follow up with you on next steps and answer any additional questions you may have. The iECHO portal is what we use to set up and manage our hosted sessions.