Resources
ARC provides patients and healthcare professionals with the latest, up-to-date resources to
help improve treatment and care of patients with amyloidosis.
Publications
Pathway for Development and Validation of Multi-domain Endpoints for Amyloid Light Chain (AL) Amyloidosis
Signorovitch J, Zhang J, Brown D, Dunnmon P, Xiu L, Done N, Hsu K, Barbachano Y, Lousada I. Pathway for Development and Validation of Multi-domain Endpoints for Amyloid Light Chain (AL) Amyloidosis. Ther Innov Regul Sci. 2024 Jul;58(4):600-609. doi: 10.1007/s43441-024-00641-6. Epub 2024 Apr 17. PMID: 38632158; PMCID: PMC11169055.
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Publications
Publications
Renal Response Criteria for Clinical Trials in Amyloid Light Chain Amyloidosis
Leung N, Comenzo R, Gillmore J, Havasi A, Kastritis E, Guthrie S, Signorovitch J, Heath D, Lousada I; Amyloidosis Forum Working Group Participants. Renal Response Criteria for Clinical Trials in Amyloid Light Chain Amyloidosis. Kidney Int Rep. 2024 Apr 4;9(7):1986-1994. doi: 10.1016/j.ekir.2024.03.033. PMID: 39081759; PMCID: PMC11284377.
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Publications

Webinars
Hereditary ATTR Amyloidosis
Wild-Type Amyloidosis
Hereditary ATTR Amyloidosis
Wild-Type Amyloidosis
Clinical Trial Updates for the ATTR Community
ARC Executive Director of Research Kristen Hsu presented the most current updates for the clinical trial landscape, with a focus on ATTR amyloidosis. Kristen will discussed the direction of future research. The webinar concluded with a Q&A session.
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Webinars

AL Amyloidosis
Webinars
Hereditary ATTR Amyloidosis
Wild-Type Amyloidosis
Other Types of Amyloidosis
Webinars
Hereditary ATTR Amyloidosis
Wild-Type Amyloidosis
Other Types of Amyloidosis
Coffee Chat with ARC
To wrap up 2024, this month’s ARC Talks Webinar consisted of a conversation with ARC staff. We shared highlights from 2024, started to look ahead to 2025, and answered your questions about the work we do for the amyloidosis community.
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AL Amyloidosis

AL Amyloidosis
Webinars
Hereditary ATTR Amyloidosis
Wild-Type Amyloidosis
Other Types of Amyloidosis
Webinars
Hereditary ATTR Amyloidosis
Wild-Type Amyloidosis
Other Types of Amyloidosis
Caring for the Caregiver
In honor of National Family Caregivers Month, ARC hosted a discussion between Debra Ruehlman, amyloidosis family caregiver, and Ann Payne, MSW, ARC Clinical Care and Education Manager. This webinar explored topics such as self care, self advocacy, and community resources.
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AL Amyloidosis

AL Amyloidosis
Webinars
Hereditary ATTR Amyloidosis
Wild-Type Amyloidosis
Other Types of Amyloidosis
Webinars
Hereditary ATTR Amyloidosis
Wild-Type Amyloidosis
Other Types of Amyloidosis
Medicare and the Evolving Financial Landscape
Covering information on Medicare basics, choosing a Part D plan, and coverage gaps, ARC was joined by Sylvia Gary from the Centers for Medicare and Medicaid Services (CMS).
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AL Amyloidosis

AL Amyloidosis
Webinars
Webinars
Clinical Trial Updates for the AL Community
ARC's own Kristen Hsu presented the most current updates for the clinical trial landscape, with a focus on AL amyloidosis. Kristen also discussed the direction future research.
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AL Amyloidosis

Library
Hereditary ATTR Amyloidosis
Patients
Hereditary ATTR Amyloidosis
Patients
Understanding Genetics in Hereditary ATTR Amyloidosis
There are over 120 different mutations that have been identified in the TTR gene and as research continues, it is possible that more may be discovered. Each mutation causes a different pattern of disease onset, symptoms and outlook.
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Library